If symptom aid not received right after third administration, adjunctive therapy appropriate for the problem is suggested Discontinuation or dosage reduction
Utilizing this drug, even as prescribed, can cause Bodily dependence and withdrawal when you quit taking the drug all of a sudden. Withdrawal is usually lifetime threatening.
Only caregivers who are deemed proficient to acknowledge seizure episodes suited to cure, make the decision to initiate remedy, administer the drug, keep an eye on the patient, and assess adequacy of response should really administer diazepam rectal gel.
Individuals suspected of remaining dependent on benzodiazepine medication ought to be incredibly gradually tapered from the drug. Withdrawals might be life-threatening, specially when extreme doses have already been taken for extended amounts of time.
You shouldn’t drink grapefruit juice when having diazepam. It may well end your liver from processing this drug accurately, leading to much more of it to stay in The body for longer. This will enhance your hazard for Negative effects.
aprepitant will raise the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Long-term day by day use as an anticonvulsant may perhaps enhance the frequency and/or severity of tonic-clonic seizures; may perhaps necessitate increase in dosage of other anticonvulsants. (See Prescribing Restrictions underneath Dosage and Administration.)
armodafinil will reduce the level or click here result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Taking sure antiseizure medication with diazepam can improve your chance for drowsiness or sleepiness. It may also result in your breathing to decelerate or halt. These here prescription drugs include things like:
diazepam will raise the amount or influence of finerenone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Observe serum potassium during initiation and dosage adjustment of both finererone or weak CYP3A4 inhibitors. Alter finererone dosage as necessary.
Individuals with chronic lung illness or unstable cardiovascular conditions really should be specified this drug with Extraordinary caution.
Constantly consult your get more info Health care company to be certain the data displayed on this page relates to your own situations.
In the event you’re taking diazepam being an increase-on therapy for treating seizures, you might have a higher dosage within your other seizure medications. This drug may perhaps lead to extra Regular and even more extreme seizures. Should you suddenly prevent taking diazepam, you might briefly have additional seizures.
Discard Diastat and Diastat AcuDial rectal delivery methods and all unused elements in the rubbish in a safe place clear of little ones; don't reuse.